Roxanne Shanté was the brassiest female rapper of the era – “I’m conceited, never beated, never heard of defeated – and Kool G Rap could destroy all-comers: “You can’t replace me, ice me or ace me/ Bass me, face me, slice me or race me/ Bite me or taste me/ I’ll show you I got force./ My rap burns your mouth like hot sauce./ Run for water while I break your tape recorder/ Server to sucker: the order is manslaughter.” Rakim was the first master of the clever lyrical brag (“My intellect wrecks and disconnects your cerebral cortex…”). (“Well, my name is known all over the world/ By all the foxy ladies and the pretty girls …”) As teenagers, we were particularly amused by Big Bank Hank’s brag about wooing Lois Lane away from Superman: “He can’t satisfy you with his little worm/ But I can bust you out with my super sperm.”Īs hip-hop progressed out of its good-time beginnings, the boasting became more skillful and inventive, the verbal flows more dexterous. Half of my schoolmates knew all the lyrics to ‘Rapper’s Delight’ by the Sugarhill Gang (1979), and it was fun to violate English modesty codes by reciting them. Then the first hip-hop records crossed the pond, and we discovered that American boast- ing could be highly entertaining when rhymed by an MC over a beat. A theory circulated among my peers that all Americans were wankers, and that was the reason they found it so difficult to under- stand the meaning of ‘wanker’. They were full of themselves, they were putting on airs, they were posers, wankers, flash gits, show-offs, bigmouths, know-it-alls.Īmericans, by contrast, were known to be loud and boastful and, worse, to take themselves seriously. There was a lexicon for people who showed insufficient modesty. S orry, would you mind… Sorry, do you think I might… Sorry, but you’re standing on my foot. It was poor form to express self-satisfaction after taking an exam, winning a prize, or really for doing anything at all.Īpologising for the inconvenient fact of your existence, on the other hand, was accepted British self-deprecation. Any attempt at ‘showing off ’ was brutally demolished by sarcasm. Send us feedback about these examples.In west London, where I grew up in the late 1970s and early 1980s, the idea of boasting about yourself was almost unthinkable. These examples are programmatically compiled from various online sources to illustrate current usage of the word 'brag.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. 2021 Lays down brag-worthy numbers, draws every eye, amazing value. Spencer Kornhaber, The Atlantic, 5 Sep. 2021 Extremely familiar forays into bass-heavy brag rap, whooshing R&B, and Afrobeats break up the slog. Times newsletter about the outdoors in Southern California. 2021 The Wild Insulated Water Bottle Allow us to humble- brag about The Wild water bottle with the cool logo of the L.A. 2022 This will also give you a brag bank to pull from when the interviewer asks you to articulate your strengths. 2022 Now, after the latest iteration of Kellyoke on the Kelly Clarkson Show, the host can add performing the knockout collaboration live alongside the country icon herself to her list of brag-worthy accomplishments. 2023Īdjective The benefits of a brag book Part of growing your salary comes with asking for a raise, which Tu believes most workers aren’t asking for often enough. 2023 In some of them, the officers bragged about making up evidence and beating up suspects. Patrick Bedard, Car and Driver, 19 Aug. 2023 Porsche brags of a new way of managing deflection steer in the rear wheels. 2023 With the financial aid office, students shouldn’t brag or boast about grades. Michael Hiltzik, Los Angeles Times, 29 Aug. 2023 During the debate, DeSantis also bragged about opening Florida’s schools during the pandemic. 2023 So just by the numbers, Biden should have a lot to brag about. Minnah Arshad, The Courier-Journal, 29 Aug. 2023 How to protect yourself While some used to brag about battling through a flu to get to work, that's no longer a badge of pride, Lockard said. 2023 The senior quarterback was not in the mood for any bragging or taking a victory lap. Hillary Maglin, Travel + Leisure, 8 Sep. Verb Brands are typically proud of their sustainability and brag about it in their product descriptions - so watch out for unsubstantiated claims and non-demonstrated impact.
0 Comments
Arc minutes, arc seconds, degrees, radians, revolutions, turnsĪcres, ares, barns, cricket pitches, dunams, football fields, football pitches, hectares, pings, Planck areas, sections, sqcm, sqkm, sqm, sqmm, square centimeter, square feet, square inch, square kilometer, square meter, square millimeter, square yards, stokes, survey townshipsĪlgerian dinars, Argentine pesos, Australian cents, Australian dollars, Bahrain dinars, Bolivian bolivianos, Botswana pula, Brazil reais, British pounds, Brunei dollars, Bulgarian levs, Canadian cents, Canadian dollars, Cayman Islands dollars, Chilean pesos, Chinese yuan, Colombian pesos, Costa Rican colones, Croatian kuna, Czech koruna, Danish kroner, Dominican pesos, Egyptian pounds, Estonian kroons, Eurocents, Euros, Fiji dollars, Honduran lempiras, Hong Kong dollars, Hungarian forints, Indian rupees, Indonesian rupiahs, Israeli shekels, Jamaican dollars, Japanese yen, Jordanian dinars, Kazakh tenge, Kenyan shillings, Kuwaiti dinars, Latvian lats, Lebanese pounds, Lithuanian litas, Macedonian denari, Malaysian ringgits, Mauritian rupees, Mexican pesos, Moldovan leu, Moroccan dirhams, Namibian dollars, Nepalese rupees, Netherlands Antilles guilders, New Zealand dollars, Nicaraguan cordobas, Nigerian naira, Norwegian kroner, Omani rials, Pakistan rupees, Papua New Guinean kina, Paraguayan guaranies, Peruvian nuevos soles, Philippine pesos, Polish zloty, Qatar riyals, Romanian lei, Russian rubles, Salvadoran colones, Saudi riyals, Seychelles rupees, Sierra Leonean leones, Singapore dollars, Slovak koruna, South African rands, South Korean won, Sri Lankan rupees, Swedish kronor, Swiss francs, Taiwan dollars, Tanzanian shillings, Thai baht, Trinidad dollars, Tunisian dinar, Turkish liras, Ugandan shillings, Ukrainian grivnas, United Arab Emirates dirhams, Uruguayan pesos, U.S. So the general idea of a pore vacuum is exactly what it sounds like: It “vacuums” your pores, suctioning out all your blackheads, ooey-gooey grossness, secrets, soul, etc. TBH, I'd say most inexpensive pore vacuums are generally the same, but I loved that this came with five attachment heads and a set of blackhead extractor tools,"-BG What does a pore vacuum do? Upon first try, the suction took some getting used to-yup, I have hickeys on my face to prove it-but once I figured out that I needed to use a lighter pressure, I started extracting a few blackheads that were ready to come the heck out. "After I first was bombarded by TikToks of people sucking major grime out of their pores, I did a deep Amazon search for the best pore vacuum and came across this one. ✔️ FYI: We updated this article in August 2023 to give you the most up-to-date info on pore vacuums, including a new one our editors tried and loved, a dermatologist’s take on blackhead removers, and how to choose the best pore vacuum for yourself. Keep scrolling for all the details you ever wanted to know about pore vacuums (including how they work and if they’re safe), along with two editors’ experiences testing the top-rated pore vacuums on the market. But I still decided to find out for myself if pore vacuums actually work to unclog pores, or if it’s all a big internet scheme. Her results were, uh, interesting at best (see below). Low key, I had some prior skepticism about pore vacuums after former Cosmo deputy beauty director Chloe Metzger chatted with dermatologist Arash Akhavan, MD, and tried one for herself. So when I saw that pore vacuums were going viral on TikTok and became the “it” blackhead remover device on social media, I absolutely had to do some investigating and testing for myself. DIY microcurrent devices? Oh yeah, I've got one of these too. Microdermabrasion devices? I've got thoughts. If you are not satisfied with the products you receive, you can also take advantage of AliExpress's free returns and exchanges within a certain time frame.Part of my job as Cosmo's beauty editor is to test every skincare device and tool that comes across my desk or social feeds. When you shop blackhead extractor tools on AliExpress, you can enjoy the convenience of free delivery and receive your favourite blackhead extractor tools faster. And not only will you save money if you buy blackhead extractor tools from AliExpress, but the quality of the blackhead extractor tools you buy will be excellent. The wide range of products sold on AliExpress is not only of the highest quality, but also at low prices. Not only can you buy blackhead extractor tools on AliExpress, but you can also buy other products at a great price. Want to enjoy even more discounts? All you have to do is simply explore AliExpress and you'll find plenty of discount Coupons so you can get the products you want at really amazingly low prices! So, please enjoy amazing discounts on your favourite blackhead extractor tools at AliExpress!īuy blackhead extractor tools at low prices and enjoy great service on AliExpress. If you’re a new user on AliExpress, don't forget to take a moment to check out the coupons before completing your order and you'll save even more on blackhead extractor tools. You can check out special promotions such as holiday sales, 11.11 Global Shopping Festival, which will give you discount coupons to save more money on your favourite blackhead extractor tools. It only takes a few seconds to complete a transaction.Įnjoy amazing discounts on blackhead extractor tools at AliExpress! Completing blackhead extractor tools purchases on AliExpress is very easy. You will find the best-selling blackhead extractor tools on AliExpress! And at AliExpress you can see the most honest reviews left by other customers, which will help you choose the best blackhead extractor tools. Here you can also find other facial care tools! Search for blackhead extractor tools on AliExpress and sort them by order. The blackhead extractor tool uses high-tech vacuum suction technology to remove blackheads, acne, lipids, etc. Are you still worried about the blackheads on your face? Then you must try these blackhead extractor tools! The blackhead extractor tool is made of durable abs material and is very safe to use. Tricyclic antidepressants are an older type of antidepressant medication that doctors do not commonly prescribe because they carry a higher risk of side effects than other drugs. Some examples include mirtazapine (Remeron) or maprotiline (Ludiomil). They are not as common as the above medications, but doctors may prescribe them for treatment-resistant depression. Tetracyclic antidepressants are a class of noradrenergic and specific serotonergic antidepressants. MAOIs can target one or multiple neurotransmitters, such as serotonin, dopamine, and norepinephrine. SNRIs can treat anxiety, depression, and some forms of chronic pain. These include vortioxetine ( Trintellix, formerly Brintellix) or vilazodone ( Viibryd). Some newer SSRIs also affect other serotonin receptors. SSRIs allow more serotonin - the “happy” hormone - to circulate in a person’s brain. This could include two different antidepressants or, in some cases, an antidepressant with a mood stabilizer or antipsychotic. Some people may need a combination of drugs to best manage their condition. The first line of treatment for depression is antidepressant medication. Some of these include aripiprazole (Abilify) and quetiapine (Seroquel). Some people with the condition may benefit from taking some types of antipsychotics that doctors prescribe “off-label.” This is when a doctor prescribes a drug for a different use than the one stated when it was licensed. AntipsychoticsĬurrently, trifluoperazine is the only antipsychotic with approval from the Food and Drug Administration (FDA) for treating anxiety. A 2020 study says that some of these medications include gabapentin (Neurontin) and pregabalin (Lyrica). There is limited research on using these medications for anxiety, but doctors may prescribe them for people who cannot take benzodiazepines. Some anticonvulsants, which are drugs people use to treat epilepsy, may also be effective in managing anxiety symptoms. This medication subclass includes medicines such as: While there is some risk of addiction to benzodiazepines, the study’s authors argue that this risk has been overstated and only applies to people with a history of substance misuse. According to a 2021 study, they can benefit people with anxiety. Some of these drugs include:īenzodiazepines, commonly called “benzos,” are a sedative. Research shows that selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs), commonly known as antidepressants, can also be effective in treating anxiety disorders. They include antidepressants, benzodiazepines, epilepsy drugs, and more. There are various medications available for the treatment of anxiety. The people are real, the case is real, the place is real, and yet Killing Fields has the veneer of fiction to it-partly due to the natural tendency of human beings to view themselves as characters in their own stories, but also due to some unfortunately heavy-handed production choices.įor one thing, it’s hard not to notice how characterly the two leads are. Angelo, is hoping to keep the promise he made to Boisfontaine’s mother to find her killer. In August last year, her case was reopened, and Sanchez, with the help of a younger detective, Aubrey St. The six-episode documentary series revolves around Detective Rodie Sanchez, who’s come out of retirement to work a cold case he failed to solve back in 1997: A young woman named Eugenie Boisfontaine had been missing for three months before her body was found in a bayou with signs of blunt-force trauma to the head. Killing Fields follows an active homicide investigation unfolding amid the sinister terrain of the Creole State, most recently romanticized by the first season of True Detective. The team feels confident that they have enough evidence to finally make an arrest and put Tommy Francise behind bars as they prepare and present their case to the DA's office.Hence the show’s title. In 2002, a murderer strikes George Barrett, one of Detective Rodie Sanchez's confidential informants, dead in his home, and Rodie suspects George's employer, Tommy Francise. With a search warrant in hand, the sheriff's office gears up to serve the warrant and search Tommy's home. The detectives look for physical evidence that links Tommy Francise to the murder of Curtis Smith, as they continue their investigation with only a confession. Rodie works on the unsolved killing of Eugenie Boisfontaine, while he prepares to investigate a second cold case that involves a young black man, who went missing in 1991.ĭetectives continue searching for physical evidence related to the unidentified body in the barrel, while awaiting DNA results from a tooth found on the corpse. The detectives continue to investigate the homicide case of Eugenie Boisfontaine, and comb through evidence in search of a motive. In the Season 1 finale, Detectives narrow their focus and obtain a subpoena for a possible lead in this homicide investigation. The detectives use cutting edge DNA technology to identify Eugenie's killer.Īubrey interviews a convicted felon while following up on a tip Rodie attempts to talk with Eugenie's ex-husband, Michael Schmidt, while rekindling his relationship with his family. Rodie and Aubrey search for witnesses who may have seen the victim before her death get a glimpse into Rodie Sanchez and Aubrey St. Episodes Season 1 (2016) No.Ī cold case in Louisiana is investigated by a retired detective in the series opener of crimes where science and technology are used to examine and resolve the mysteries.ĭetectives from Iberville Parish Sheriff's Office utilize technology to investigate DNA evidence from the crime scene. On February 2, 2016, Discovery Channel ordered a minimum of 6 more episodes. Suspects during the investigation featured in the show were: Derrick Todd Lee, also known as the Baton Rouge Serial Killer, an unidentified male named Robert that Eugenie may have dated at the time of her murder and Michael Schmidt, her ex-husband. Both detectives are joined by many other detectives in the Iberville Parish Sheriff's office. His father worked with Sanchez for many years before he retired. Angelo is a young detective who is helping Sanchez on the case. Because he could never stop thinking about it, he came out of retirement to try to solve the crime. Was it a singular murder or from a string of serial murders in the area? (There were 60 cases of missing and murdered women in the area during that time period and several serial murderers lived in nearby Baton Rouge.)ĭetective Rodie Sanchez was the first investigator assigned to the case in 1997. Her body was found three months later in Bayou Manchac in nearby Iberville Parish, 15 miles south of Baton Rouge. In June 1997 in Baton Rouge, Louisiana, Eugenie Boisfontaine disappeared. The show is executive produced by Barry Levinson and Tom Fontana among others. This is the first true crime series developed by Discovery. The show follows the investigators in real time as they try to solve the crime, which took place in June 1997. In 2016, the Discovery Channel began a series called "Killing Fields" about a cold case in Louisiana. Killing Fields is a cold case television series which premiered in 2016 on Discovery Channel. It features real-time scoring in musical notation, supporting guitar tablature, chord abbreviations and drum notation. Logic Pro can work with MIDI keyboards and control surfaces for input and processing, and for MIDI output. Logic Express only handled up to 255 audio tracks, depending on system performance ( CPU and hard disk throughput and seek time), while, as of version 10.4.5, Logic Pro can handle up to 1000. Logic Express was limited to two-channel stereo mixdown, while Logic Pro can handle multichannel surround sound. Logic Pro and Express once shared many functions and the same interface. It also supports Apple Loops – royalty-free, professionally recorded instrument loops. Logic Pro provides software instruments, audio effects and recording facilities for music synthesis. In May 2023, Logic Pro for iPad was introduced and is available since May 23. On December 8, 2011, the boxed version of Logic Pro was discontinued, along with Logic Express, and as with all other Apple software for Macs, Logic Pro is now only available through the Mac App Store, or with a discounted Pro Apps for Education Bundle for students through the Apple Store online. Apple's GarageBand comes free with all new Macintosh computers and iOS devices and is another application built on Logic's audio engine. Ī consumer-level version based on the same interface and audio engine but with reduced features, called Logic Express, was also available at a reduced cost. It is the second most popular DAW – after Ableton Live – according to a survey conducted in 2015. Apple acquired Emagic in 2002 and renamed Logic to Logic Pro. It was originally created in the early 1990s as Notator Logic, or Logic, by German software developer C-Lab which later went by Emagic. Logic Pro is a proprietary digital audio workstation (DAW) and MIDI sequencer software application for the macOS platform developed by Apple Inc. MIDI sequencer and digital audio workstation For Windows: VST2 & VST3 plug-ins can be hosted.X86-64 (as of Logic Pro 9.1) ARM64 (as of Logic Pro 10.6).For Apple Silicon Macs running RX natively: AU & VST3 plug-ins can be hosted.For Intel Macs, and Apple Silicon Macs running RX in Rosetta: AU, VST2, & VST3 plug-ins can be hosted.VST3 support is brand new in RX, and we'd love to hear your feedback! Click Help > Give Feedback in the RX Audio Editor to let us know if any plug-ins aren't working.RX 10 Elements consists of plug-ins only, the RX 10 Audio Editor application is not included with RX 10 Elements. Logic Pro 10.6.3 - 10.7.x, Pro Tools 2021 - 2022, Ableton Live 11, Cubase 11 - 12, Nuendo 12, Studio One 5, Reaper 6, FL Studio 20, Audition CC 2022, Premiere Pro CC 2022. Repair Assistant plug-in available as Audiosuite only in Pro Tools and VST3 & AU formats in other DAWs.Ambience Match, Dialogue Isolate and De-rustle plug-ins are AAX Audiosuite for Pro Tools only.Spectral Editor & Music Rebalance ARA plug-ins are available in Logic Pro on Intel or Apple silicon Macs (in Rosetta only).RX 10 plug-ins are not available in VST2 format.Plug-in Formats:ĪU, AAX, AAX Audiosuite*, VST3, AU ARA*. *Supported on Intel Macs & Apple silicon Macs (M-series chips) in Rosetta and native. Selina reveals to Batman that Falcone is her father. Alfred believes that Falcone had Thomas and Martha killed to silence them. Bruce confronts Alfred, who maintains that Thomas only asked Falcone to threaten the journalist into silence Thomas planned to turn himself and Falcone over to the police once he found out Falcone murdered the journalist instead. The Riddler leaks evidence that Thomas, who was running for mayor before he was murdered, hired Falcone to kill a journalist who was writing a story about Martha's family history of mental illness. Bruce's butler and caretaker, Alfred Pennyworth, is hospitalized after opening a letter bomb addressed to Bruce. After a car chase, Batman captures the Penguin, but he and Gordon learn the Penguin is not the informant.īatman and Gordon follow the Riddler's trail to the ruins of an orphanage funded by Bruce's murdered parents, Thomas and Martha Wayne, where they learn that the Riddler holds a grudge against the Wayne family. Selina inadvertently exposes them when she arrives to steal money and discovers Annika's corpse in the trunk of a car. They discover that Maroni's operation transferred to Falcone, with many corrupt GCPD officers involved. Batman and Gordon deduce that the informant may be the Penguin and track him to a drug deal. Colson refuses to answer the third-the name of the informant who gave the GCPD information that led to a historic drug bust ending gangster Salvatore Maroni's operation-and is killed. When Batman arrives, the Riddler calls him via Colson's phone and threatens to detonate the bomb if Colson cannot answer three riddles. The Riddler abducts Colson, straps a timed collar bomb to his neck, and sends him to interrupt Mitchell's funeral. When Annika disappears, Batman sends Selina to the Iceberg Lounge for answers and discovers that Savage was on Falcone's payroll, as is district attorney Gil Colson. While the Penguin pleads ignorance, Batman notices that Selina Kyle, Annika's roommate, works at the club as a waitress. The following night, the Riddler kills Commissioner Pete Savage and leaves another message for Batman.īatman and Gordon discover that the Riddler left a thumb drive in Mitchell's car containing images of Mitchell with a woman, Annika Kosolov, at the Iceberg Lounge-a nightclub operated by Oswald "The Penguin" Cobblepot, crime boss Carmine Falcone's lieutenant. Lieutenant James Gordon discovers a message that the Riddler left for Batman. Reclusive billionaire Bruce Wayne, who has operated for two years as the vigilante Batman, investigates the murder alongside the Gotham City Police Department (GCPD). is murdered by the Riddler, a masked serial killer. On Halloween, Gotham City mayor Don Mitchell Jr. The first sequel, titled The Batman – Part II, is set for release on October 3, 2025. The Batman is intended to launch a Batman shared universe, with two sequels planned and three spin-off television series in development for Max, which include The Penguin starring Farrell. The film was nominated for three awards at the 95th Academy Awards, and received numerous other accolades. The film was a commercial success, grossing $771 million against a $185–200 million budget, making it the seventh-highest-grossing film of 2022, and received positive reviews from critics. It resumed later in the year and concluded in Chicago in March 2021.Īfter the COVID-19 pandemic caused two delays to its original June 2021 release date, The Batman premiered at the Lincoln Center in Manhattan on March 1, 2022, and was theatrically released on March 4. Filming began in the United Kingdom in January 2020, but was halted in March by the COVID-19 pandemic. Pattinson was cast in May 2019, with further casting in late 2019. He sought to explore Batman's detective side more than previous films, drawing inspiration from the films of Alfred Hitchcock and the New Hollywood era, and comics such as " Year One" (1987), The Long Halloween (1996–97), and Ego (2000). Reeves took over and reworked the story, removing the DCEU connections. Affleck signed on to direct, produce, co-write, and star in The Batman, but had reservations about the project and dropped out. The film sees Batman, who has been fighting crime in Gotham City for two years, uncover corruption while pursuing the Riddler (Dano), a serial killer who targets Gotham's corrupt elite.ĭevelopment began after Ben Affleck was cast as Batman in the DC Extended Universe (DCEU) in 2013. It stars Robert Pattinson as Bruce Wayne / Batman alongside Zoë Kravitz, Paul Dano, Jeffrey Wright, John Turturro, Peter Sarsgaard, Andy Serkis, and Colin Farrell. The film was directed by Matt Reeves, who wrote the screenplay with Peter Craig. Pictures, it is a reboot of the Batman film franchise. Pictures, DC Films, 6th & Idaho, and Dylan Clark Productions, and distributed by Warner Bros. The Batman is a 2022 American superhero film based on the DC Comics character Batman. Just be sure to remove them from the turner and lay them on the floor of the incubator (most come with a wire floor) three days before hatch. If you are using an automatic egg turner, then that will take care of the turning for you. Keep the incubator closed during hatching to maintain proper temperature and humidity. The embryos are moving into hatching position and need no turning. Do not turn eggs during the last three days before hatching. Many experts say if you can turn them 4-5 times a day it is even better. Follow the instructions above and the further details you will find in your incubator's instruction guide.Įggs must be turned at least 2-3 times daily during the incubation period. Many experts agree that a common cause of poor hatch rates is TOO MUCH humidity during the first part of incubating and NOT ENOUGH during the last three days (the "lock-down" period). This will increase the surface area that is wet, allowing more water to evaporate into the air which increases the humidity. This will not hurt the incubator, though it sure makes it easier to tell if you have enough water!Īnother Tip: Having a hard time getting the humidity high enough? Try placing small sponges inside the incubator. In the Little Giant, this will color the foam. It will change again when the water channel is actually dry. As the water level decreases, you'll notice the color of the water (due to the food coloring) start to darken. Humidity Tip: If you find that you are having a difficult time seeing the water in the channels to know if there is enough water, try this little trick: just add a drop or two of food coloring to the water. Check the water level periodically to ensure they don't dry out. Please note that the humidity in your area will have an impact on how much water you'll need in the incubator to keep it within the correct humidity range. Follow the instructions that come with the incubators. The Little Giant and Hova-Bator incubators come with simple instructions on how to use the water channels in the floor of the incubator. Keeping an adequate humidity range inside your incubator is quite simple. During the last three days (the "lock-down" period), the humidity level should be increased to between 70-80%. The ideal humidity level for hatching eggs is still being debated among experts, but many agree that it should not fall below 25% or above 60% between setting and three days prior to hatching. Humidity is controlled in order to prevent unnecessary loss of egg moisture. Abrupt warming from 55 degrees to 100 degrees can cause moisture condensation on the egg shell which can lead to disease and reduced hatches. Allow cool eggs to warm slowly to room temperature before placing in the incubator. Eggs have the best hatch rate when stored for no more than 7 days before beginning to incubate. Myocardial infarction (MI) was diagnosed based on the 3rd universal definition of MI. Therefore, the final dataset included 442 patients with 442 culprit lesions. We further excluded from the analysis lesions in which balloon angioplasty was required before OCT imaging or those with insufficient image quality. The exclusion criteria for OCT imaging were patients with cardiogenic shock, congestive heart failure, significant left main disease, and suboptimal results after thrombectomy with Thrombolysis in Myocardial Infarction (TIMI) 0–2 flow. Therefore, we conducted a retrospective analysis to investigate the morphological differences of culprit lesions of ACS between patients with and without prior ASA use at their first presentation of ACS.įrom a total of 1,150 patients with ACS treated with percutaneous coronary intervention (PCI) at Tsuchiura Kyodo General Hospital between October 2008 and December 2015, we identified 511 patients with their first presentation of ACS who underwent OCT examinations of the de novo culprit lesion at the time of PCI. Optical coherence tomography (OCT) is an unprecedented imaging modality, which enables in vivo assessment of coronary plaque and intracoronary thrombus with near-pathology resolution. Of note, the effect of prior ASA use on the local pathogenesis of culprit lesions in ACS has not been elucidated. Thus, despite clinical data and reasonable pharmacological action against thromboembolism, the effects of ASA on the presentation of first ACS continue to be debated. 2Īlthough previous reports suggested the efficacy of ASA for primary prevention in high-risk subjects with diabetes, recent studies cast doubt on this finding. Moreover, in contrast to secondary prevention, the benefit of ASA for primary prevention has been controversial. However, there remains controversy whether prior ASA use is an independent risk for worse outcomes or only a marker of different high-risk features. 1 – 3ĭespite its protective actions against coronary thrombi and its proven effectiveness in ACS patients, the prior use of ASA in advance of a presentation of non-ST-elevation ACS is reported as a high-risk feature for subsequent adverse events. With a first ACS presentation, patients with prior ASA use were more likely to present with non-ST-elevation ACS with less frequent intraluminal thrombi, but no significant difference in underlying plaque characteristics or clinical course.īased on substantial evidence, acetylsalicylic acid (ASA), also known as aspirin, has for decades been accepted as the first-line antithrombotic agent for the treatment of acute coronary syndrome (ACS) and for secondary prevention in patients with cardiovascular disease. Rate of adverse events did not differ between the ASA and the non-ASA groups in the matched cohort. 75.5%, P<0.001), whereas no significant difference was observed in plaque characteristics. OCT revealed less frequent thrombi in the ASA than in the non-ASA group in both the entire (37.3 vs. Propensity score matching yielded 49 patients in both groups. Non-ST-elevation ACS was more prevalent in the ASA than in the non-ASA group (79.1 vs. The ASA group was older, had higher frequency of dyslipidemia and hypertension, and lower renal function than the non-ASA group. 67 patients (15.2%) had received ASA at presentation. Clinical characteristics, OCT findings, and adverse events at 30 days were compared between patients with prior ASA use and ASA-naïve patients (non-ASA). In total, 442 patients with their first ACS episode undergoing OCT for the culprit lesions were investigated. This study used optical coherence tomography (OCT) to investigate the morphological features of culprit lesions of ACS in patients with prior ASA use. The effect of prior use of aspirin (ASA) on the onset of acute coronary syndrome (ACS) has not been clarified. Division of Cardiovascular Medicine, Tsuchiura Kyodo General Hospital His breakout moment came in 2013 with the acclaimed horror project “Mama,” also starring Chastain. Discovery franchise - New Line Cinema’s “It” starring Bill Skarsgard and Jessica Chastain. También se esperaba que Andy Muschietti dirigiera la segunda película, lo que luego fue confirmado. Luego de varias exitosas cintas de terror. Muschietti was the creative force behind another blockbuster Warner Bros. Mientras, el argentino Andy Muschietti sigue con incredulidad y preocupación estas noticias de su protagonista, que ya se ha enfundado el uniforme rojo de Flash en más de cinco ocasiones, tanto en cine como en TV. While the DCU exists as a multiverse, these titles will exist in one singular universe. Lesser known DC characters, including Booster Gold and Swamp Thing, will also be introduced. He is a producer and director, known for Mama (2013), It (2017) and It Chapter Two (2019). I wanted to communicate the feeling of intimacy and innocence of the Losers. Additional titles include a previously announced Superman feature written by Gunn, now officially titled “ Superman: Legacy,” a Wonder Woman prequel series and a Green Lantern mystery series. 16 Photos Andy Muschietti was born on 26 August 1973 in Buenos Aires, Federal District, Argentina. Dirección Guion para cine Producción ejecutiva On It (2017) In developing the film, I was retrieving my emotional experience reading the book. Gunn and Safran’s inaugural slate is called “Gods and Monsters,” and the content spans series and standalone films. This will mark the first live-action film appearance of Robin since Chris O’Donnell played the role opposite George Clooney in the 1997 film “Batman and Robin.” This film will exist separately from Robert Pattinson’s “The Batman” movies. The project does not currently have a screenwriter attached. They’re an extraordinary team, and we couldn’t have better or more inspiring partners as we embark on this thrilling new adventure in the DCU.” Barbara signed on to produce with us and we were on our way. 16 Photos Andy Muschietti was born on 26 August 1973 in Buenos Aires, Federal District, Argentina. So, when it came time to find a director for ‘The Brave and the Bold,’ there was really only one choice. Amber Heard confirms her split from Vito Schnabel as shes seen sharing a passionate kiss with director Andy Muschietti. Muschietti finalized a deal to direct The Brave and the Bold, the feature project that will introduce a new big-screen version of Batman, one that will fit into the expansive universe being. “It’s a magnificent film – funny, emotional, thrilling – and Andy’s affinity and passion for these characters and this world just resonates through every frame. “We saw ‘The Flash’ even before taking the reins at DC Studios, and knew we were in the hands of not only a visionary director but a massive DC fan,” Gunn and Safran told Variety of Muschietti. Andrs Muschietti is a director, screenwriter and producer of film and television Argentina, graduated from the University of the cinema of Buenos Aires. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |